IUI

Modern unhealthy life styles, hectic work schedules, stress factors and an improper diet have all contributed to Fertility problems. ‘1 in 6 couples face a fertility issue now’

To override fertility problems, IUI (Intrauterine Insemination) method is employed. IUI is an in-vivo technique wherein a Sperm from a Donor or Partner is placed into the female’s uterus using a flexible and thin sterile catheter to facilitate natural Fertilization.

Why is it done?

IUI technique is used when:

  • Male has low sperm count mild to moderate (Oligospermia)
  • A female has a dysfunctional cervix, cervical mucus problem, or unfavourable uterine condition
  • A male is suffering from Retrograde Ejaculation (releasing semen & sperms into the urinary bladder rather than out of the penis)
  • A man is suffering from Erectile Dysfunction (inability to maintain an erection)
  • During infertility that has ‘no apparent reason’; unexplained fertility
  • A female is suffering from mild endometriosis (when endometrium tissue lining grows outside the uterus causing pain and bleeding)

Donor sperm is used in IUI when-

  • Male partner suffers from Sexually Transmitted Disease (STD) or Genetic disease.
  • A female wants to get pregnant without any intercourse with a male partner.
  • A male is sterile (Azoospermia) or has a negligible sperm count (oligospermia).

When & How is it done?

  • It is useful in females under 35-40 years of age.
  • Medicines that stimulate Ovulation (release of eggs) are administered.(Natural ovulation is also an option wherein no fertility drugs are used.)
  • Meanwhile, sperms are washed off and concentrated with the healthiest sperms to ensure fertilisation.
  • After 24-36 hours of the rise in Luteinizing Hormone (LH), that indicates imminent ovulation, IUI is done.
  • The sperms are injected using a flexible catheter directly into the uterus. This is a quick process and induces minimal to no pain.
  • A Pregnancy Test, to confirm the pregnancy, is done after two weeks from insemination.

Risks Associated:

  • Slight risk of infection in Uterus and fallopian tubes is possible due to-
    • Contaminated semen sample, or
    • Contamination of sterile catheter in cervical/vaginal area.
  • Multiple Pregnancy risks; Conceiving twins or more.
  • Puncture in the uterus during IUI process.

Benefits of IUI-

IUI (Artificial Insemination) technique has numerous benefits like-

  • A female can conceive a child without any intercourse with a male if it is painful or undesired by her.
  • It enables the couples to experience parenthood who have a low sperm count or a poor sperm quality.
  • This technique is less expensive, $300-$800, as compared to IVF (In-vitro Fertilization) technique, $12,000. These are the US Figures.
  • It is close to the natural method of fertilisation.
  • It is a less invasive technique and takes barely few minutes.

 Success Rates for IUI:

Success Rates are subject to the factors like female age, the reason for infertility, sperm quality.

  • A female over 41 years old will have an extremely low success rate of getting pregnant with IUI method. Therefore, she should opt for aggressive pregnancy methods like IVF.
  • In a case of unexplained infertility, female under 35 years of age and male having healthy sperm, will have these success rates-
    • 10% chance/month of a successful pregnancy using IUI (up to 3 cycles) with Clomid
    • 15% chance/month of a successful pregnancy using IUI (up to 3 cycles) with injectable FSH meds.

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